We present information on how to choose the best glucosamine supplement and then give a list of the ten best ones available on the market today. Some factors considered in the article are ingredients, value, the amount per serving, and delivery method.

Glucosamine is the second most widely used supplement on the market today.

In young, healthy joints, glucosamine, an amino sugar, helps keep your cartilage healthy, and that healthy cartilage cushions your bones at your joints. As you age, the natural amounts of glucosamine go down, and cartilage and joints begin to deteriorate. While the highest concentrations of glucosamine are in your joints, it can also be found all over other parts of your body.

Supplements can give you more of the glucosamine your body is no longer producing or retaining well. Normally, the best way to get more of a naturally-occurring supplement is to find food that contains the nutrient and get it that way, but there are no natural food sources that contain glucosamine; so if you want to get more of it, a supplement is the only way.

People have joint pain for all types of reasons, including overuse, injuries, and arthritis.

We also have joints all over our bodies, so painful joints can end up interfering with a wide range of activities, including some of the most basic ones of daily living. There is a widespread need to find a supplement that can help reduce that pain.

Additionally, some people choose to take glucosamine supplements as a preventive measure to keep their joints healthy before any deterioration takes place and to reduce the risk of injury.

Studies have shown that those taking glucosamine have improved function and reduced pain over those taking a placebo, but they don’t always work for everyone, and more research is needed.

How We Chose Our Ratings

There are a lot of glucosamine supplements on the market, so choosing the best one to use can be overwhelming.

We have taken the guesswork out of the decision by looking at a wide range of products on the market right now and selecting our top 10.

Furthermore, we looked at overall product ratings, customer reviews, what ingredients make up the product, and overall value to determine the list we present here. Then we broke down the important features of each product so that you can decide which is the best for you.

Product

Image

Quality

Price

1. Schiff Glucosamine 2000 mg with Hyaluronic Acid, 150 tablets

Schiff best glucosamine

2. Kirkland Signature Extra Strength Glucosamine HCL 1500 mg, With MSM 1500 mg, 375 tablets

Kirkland Signature best glucosamine

3. Puritan’s Pride Glucosamine Sulfate 1000 mg, 240 capsules

Puritan's Pride best glucosamine

4. NOW Glucosamine Sulfate 750 mg, 240 capsules

NOW best glucosamine

5. Solaray Glucosamine Sulfate 1500 mg, 120 capsules

Solaray best glucosamine

6.  Divine Bounty Glucosamine Sulfate Supplement (2000 mg per serving) with MSM, 240 vegetarian capsules 

Divine Bounty best glucosamine

7. Bulk Supplements Pure Glucosamine HCL Powder, 500 grams

BulkSupplements best glucosamine

8. Vimerson Health Glucosamine (1000 mg per serving) + Hyaluronic Acid + Bioperine + MSM + Boswellia – 60 vegan capsules

Vimerson Health best glucosamine

9. Jarrow Formulas Glucosamine HCl Mega, 1000 mg, 100 tablets

Jarrow best glucosamine

10. Doctor’s Best Synergistic Glucosamine MSM with OptiMSM, 1500 mg, 180 capsules

Doctor's Best best glucosamine

Top 10 Best Glucosamine Supplements

Schiff Glucosamine 2000 mg with Hyaluronic Acid, 150 tablets

Schiff best glucosamine

This product uses glucosamine HCl (hydrochloride), which contains approximately 83% glucosamine, whereas products that use glucosamine sulfate typically only contain around 65% glucosamine.

Hyaluronic acid, a natural substance present in connective and joint tissues, is included to help with the lubrication of joints.

Many customers reported having less pain in their knees and other joints both from aging and arthritis after using the product for only a couple of weeks, while others noticed that their pain returned if they stopped taking it.

Having less pain and discomfort also allowed some to resume or keep up with an exercise program or physical therapy exercises, which helped their joints even more. One customer even proclaimed feeling “10 years younger!”

  • 2000 mg per serving (two tablets), 75 servings per container

Pros

Cons

  • Reviews say that it works better than other brands
  • May raise blood pressure and cholesterol levels

Quality

Price

Rating

$$


Kirkland Signature Extra Strength Glucosamine HCL 1500 mg, With MSM 1500 mg, 375 tablets

Kirkland Signature best glucosamine

Made with glucosamine hydrochloride and boosted with sulfur, a necessary element for joint health, both of which are components of collagen, this product had thousands of positive reviews.  

Customers repeatedly report similar results of more aching and painful joints before they started the Kirkland supplement and less pain or the disappearance of pain after they started taking it. Some even said that their hair and skin looked stronger and thicker, which was an added bonus that they enjoyed. 

  • 1500 mg per serving (two tablets), approximately 187 servings per container 

Pros

Cons

  •  Reduction in Knee pain
  •  May cause increases  in ocular pressure

Quality

Price

Rating

$$


Puritan’s Pride Glucosamine Sulfate 1000 mg, 240 capsule

Puritan's Pride best glucosamine

The sulfate version of glucosamine is used in this supplement, as sulfur is considered an important component in joint health.  

A highly-rated product, one user even reported being able to stop taking his fish oil supplements that he originally had been using in conjunction with the glucosamine. For those who have trouble swallowing pills, one easy-to-swallow gel capsule contains the entire dose, whereas many comparable products require two to three large tablets to be taken each day.  

  • 1000 mg per serving (one capsule), 240 servings per container 

Pros

Cons

  • Help promote smoother and younger-looking skin
  • Some people have a sensitivity to products containing high levels of sulfur

Quality

Price

Rating

$$


NOW Glucosamine Sulfate 750 mg, 240 capsules

NOW best glucosamine

This is a glucosamine pill without any additional joint supplements added to it. Many customers said that they had less pain and less popping and crackling in their joints after taking this for one to two weeks.  

NOW Foods is a premier natural products manufacturer. They are the originator of the method used to test glucosamine that has been adopted and endorsed by AOAC International.  

AOAC International is the organization that develops voluntary consensus in testing methods for dietary supplements. 

  • 1500 mg per serving (two capsules), 120 servings per container 

Pros

Cons

  • Simple, once- a-day formula
  • Small concentrations of ingredients

Quality

Price

Rating

$$


Solaray Glucosamine Sulfate 1500 mg, 120 capsules

Solaray best glucosamine

For those looking for glucosamine without other additions, these capsules from Solaray provide another good option.  

Happy customers mention being able to dance and getting up the stairs again. A few users didn’t have joint pain when they started taking the product.

However, they noticed that they were more flexible and found physical activities easier on their joints than before they started taking it.  

Moreover, most users were using this for knee or foot pain. It is interesting to note that some even had positive results for hip and neck pain as well. 

  • 1500 mg per serving (two capsules), 60 servings per container 

Pros

Cons

  • Supports normal healthy cartilage and joint function
  • Some reviews say capsule is covered in a yellow powder that gets all over anything it touches

Quality

Price

Rating

$$


Divine Bounty best glucosamine

Divine Beauty combines glucosamine sulfate with MSM (methylsulfonylmethane) into a small capsule that is easy to swallow.  

MSM is reported to reduce inflammation and raises immunity. The dosage for this product is also on the higher end at 2000 mg for maximum benefits and efficacy. Also, while most glucosamine supplements are made from shellfish, this one contains no animal products. It is, therefore, a good option for vegetarians or vegans. Additionally, the product is gluten and soy free.  

Customers reported being able to take less pain medication and improved joint function in as little as two weeks. Others used the supplement to increase joint health for better performance and flexibility in their weightlifting routines. 

  • 2000 mg per serving (four capsules), 60 servings per container 

Pros

Cons

  • Most effective and scientifically backed nutrients that support healthy joints
  • Don't take on an empty stomach

Quality

Price

Rating

$$


BulkSupplements best glucosamine

This is the only supplement on our list that comes in powder form.  

Accordingly, this option allows you to better control how much you take and how to take it. This product provides the best value. Users also say it has little to no taste and can be dissolved in water or sprinkled on applesauce or in a smoothie. It comes in a foil zip pouch and contains no fillers.  

Many customers said they switched to the powder after taking pills for years. Some say it is because of lower cost and some wanted a product with no added ingredients. Additionally, while some supplements in pill or capsule form can upset the stomach, people stated no longer having that problem when they started using the powder form. 

  • 1000 mg per serving (1/4 teaspoon contains 1040 mg), 500 servings per container 

Pros

Cons

  • Works to protect your joints from wear and tear
  • In some instances, people also experienced fatigue and headache

Quality

Price

Rating

$$


Vimerson Health best glucosamine

This supplement is packed with ingredients that are thought to promote joint health. In addition to 1000 mg of glucosamine sulfate, they also contain hyaluronic acid and MSM. Both also exists naturally in the body. Bioperine is a black pepper extract that may promote the absorption of nutrients, and Boswellia is an extract from frankincense that is said to reduce pain.  

This option is also 100% vegan. Positive reviews from customers include claims of reduced pain and better skin. 

  • 1000 mg per serving (two capsules), 30 servings per container 

Pros

Cons

  • Made from all-natural ingredients that have been time tested and proven effective
  • It doesn’t come with mineral and vitamin fortification

Quality

Price

Rating

$$


Jarrow Formulas Glucosamine HCl Mega, 1000 mg, 100 tablets

Jarrow best glucosamine

Glucosamine HCl is naturally sodium-free. This makes it a great option for anyone with high blood pressure or who have been told to monitor her or his sodium intake. Described as a “lifesaver,” this bare bones product is both effective and a good value.  

One tablet contains the entire dose. This makes it easy to be added to your morning routine. You also do not need to worry about having to remember to take additional pills later or break up dosages. 

  • 1000 mg per serving (one capsule), 100 servings per container 

Pros

Cons

  • It may effectively reduce* joint pain and inflammation
  • Sourced from crustaceans like shrimp, crayfish, and crab thus this supplement is not safe for people with shellfish allergy

Quality

Price

Rating

$$


Doctor’s Best Synergistic Glucosamine MSM with OptiMSM,
1500 mg, 180 capsules

Doctor's Best best glucosamine

Another option which has both glucosamine sulfate and MSM. The high number of capsules per serving makes it easy to divide doses throughout the day or tailor how much one uses so that it is most effective.  

These capsules include vitamin C. In addition to its cold-fighting and general health boosting claims, it also helps your body produce collagen. The company cites numerous studies that show that subjects who used this formulation of glucosamine had better-reported results than those using placebos and those using glucosamine sulfate alone. 

  • 1500 mg per serving (six capsules), 30 servings per container 

Pros

Cons

  • Combines the top 3 joint pain relief ingredients
  • May cause abdominal cramps and bloating

Quality

Price

Rating

$$


Buyer’s Guide

Most products on the market combine several active ingredients that are thought to promote joint health to have the greatest effect. To decide whether you want a combination product or which one to try, we will tell you about some of the differences between them. We also included what factors to consider in buying a supplement. 

Which Type of Glucosamine Should You Use? 

There are two types of glucosamine: hydrochloride and sulfate.  

The hydrochloride version is generally more potent per milligram. But its ability to be absorbed may not be as good as the sulfate version. Evidence as to which one is more effective differs. It can also be affected by the additional ingredients in an individual supplement. Look at the individual product and its claims to decide which one you would like to try. 

Most glucosamine that comes as a supplement is naturally derived from the shells of crushed shellfish. They are usually from s lobsters and shrimp.  

Some people who have allergies to shellfish report being able to take natural glucosamine without problems. However, others report having some reactions. If you have an allergy to shellfish, you should consult with a doctor about whether a natural or synthetic option is best for you.  

Vegans and vegetarians may also want to opt for the synthetic versions to be able to use an animal-free product 

Should You Use a Natural or Synthetic Option? 

Most glucosamine that comes as a supplement is naturally derived from the shells of crushed shellfish. They are usually from s lobsters and shrimp.  

Some people who have allergies to shellfish report being able to take natural glucosamine without problems. However, others report having some reactions. If you have an allergy to shellfish, you should consult with a doctor about whether a natural or synthetic option is best for you.  

Vegans and vegetarians may also want to opt for the synthetic versions to be able to use an animal-free product.

How Much Should You Take? 

All the options have dosages ranging from 1000 to 2000 milligrams. However, most of the bottles suggest that you can adjust the amount you take depending on how it works for you.   

It can be easier to adjust the amount if the pills contain fewer milligrams per pill.  

In contrast, those who have trouble swallowing pills may have more trouble taking multiple pills per day. Extra glucosamine should not have ill effects. But make sure to check the other ingredients in the supplements as it may not be safe to increase your intake of those.  

Also, be sure to check with a doctor or other health professional before starting taking supplements. Or when changing the amount of a supplement you take. 

Pricing

We did not include prices for the supplements on the list because they tend to change frequently.  

Also, they may be available in different sized bottles, and can be purchased from different vendors. We did make sure to include how many pills were recommended to take and how many servings are included in each product. So that you can more easily compare the price and value across products.  

Finally, we all want healthy, flexible joints. It helps us continue a healthy lifestyle and get through the day with little or no pain. With so many options on the market today, it can be hard to choose the best glucosamine supplement to use.  Looking at the other ingredients, dosage, delivery, and value can help you decide on a supplement that is right for you.  

Whichever one you choose, we recommend checking with a health professional before you begin using it.