lmodium is a brand-name drug. lt’s available as both an over-the-counter and prescription medication. lt usually comes as a 1-mg/7.5-ml liquid, 2-mg capsule, and 2-mg tablet. Not all forms and strengths of lmodium are used in the same way, so be sure to read the label carefully before giving the medicine to your child.

The active ingredient in lmodium is the drug loperamide. lt’s used to treat symptoms of diarrhea. Loperamide works by slowing down the time it takes for food to travel through the digestive tract. This helps your child.have fewer stools. lmodium also makes their stools bulkier and less watery, which helps decrease the loss of fluids and electrolytes from their body. Electrolytes are important minerals that help with many body functions.

IMODIUM A-D

lmodium A-D has generic name loperamide with brand names Diamode, and lmodium A-D. lmodium (loperamide) slows the rhythm of digestion so that the small intestines have more time to absorb fluid and nutrients from the foods you eat. lmodium is also used to reduce the amount of stool in people who have an ileostomy (re-routing of the bowelthrough a surgical opening in the stomach).

Precautions

Avoid using lmodium

  • lf you have stomach pain without diarrhea, ulcerative colitis, bloody or tarry stools, diarrhea with a high fever, or diarrhea that is caused by a bacteria! infection or by taking antibiotic medicine.
  • More than the recommended dose of this medicine.
  • For a child younger than 2 years old. Loperamide can cause serious breathing problems and heart problems in a child.

You should not use lmodium if you are allergic to Loperamide, or if you have:

  • stomach pain without diarrhea;
  • ulcerative colitis;
  • diarrhea with a high fever;
  • stools that are bloody, black, or tarry;
  • diarrhea caused by taking an antibiotic (Clostridium difficile)
  • diarrhea that is caused by a bacterial infection.

Ask a doctor or pharmacist if it is safe for you to take this medicine if you have:

  • a fever;
  • mucus in your stools;
  • AIDS (acquired immunodeficiency syndrome);
  • a history of liver disease; or
  • if you are taking an antibiotic
  • if you are pregnant.

Loperamide can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are using this medicine.

Drink plenty of liquids while you are taking this medicine. lt may take up to 48 hours of taking lmodium before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve after L0 days of treatment.

Misuse of loperamide can cause serious heart problems that could be fatal. lmodium can also cause a serious heart problem if you use certain medicinds at the same time. Ask a doctor or pharmacist if it is safe for you to use this medicine if you are also taking other medications. lmodium may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

SIDE EFFECTS

Check with your doctor immediately if any of the following side effects occur while taking loperamide:

  • Bloating
  • constipation
  • loss of appetite
  • stomach pain (severe)with nausea and vomiting
  • skin rash

Some side effects of loperamide may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your healthcare professional may be able to tell you about ways to prevent or reduce some of these side effects such as dizziness or drowsiness, and dryness of mouth.

IMODIUM DOSAGE

ImodiumPlease note that L capsule = 2 mg. Patients should receive appropriate fluid and electrolyte replacement as needed.

For Acute Diarrhea

Adults: The recommended initialdose is 4mg (two capsules) followed by 2 mg (one capsule) after each unformed stool. The daily dose should not exceed 16mg (eight capsules). Clinical improvement is usually observed within 48 hours.

Children: ln children 2 to 5 years of age (20 kg or less), the non-prescription liquid formulation (IMODIUM® A-D t me/7.5 mL) should be used; for ages 6 to 12, either IMOD|UM@ Capsules or IMODIUM® A-D Liquid may be used. For children 2to t2 years of age, the following schedute for capsules or liquid will usually fulfill initial dosage requirements:

Recommended First Day Dosage Schedule

  • 2 to 5 years: 1 mg t.i.d. (3mg daily dose) (13 to 20 kg)
  • 6 to 8 years: 2 mg b.i.d. (4mg daily dose) (20 to 30 kg)
  • 8 to 12 years: 2mg t.i.d. (6mg daily dose) (greater than 30 kg)

Recommended Subsequent Daily Dosage

Following the firsttreatment day, it is recommended that subsequent IMODIUM@ doses (Img/LO kg body weight) be administered only after a loose stool. Total daily dosage should not exceed recommended dosages for the first day.

For Chronic Diarrhea

Children: Although IMODIUM@ has been studied in a limited number of children with chronic diarrhea; the therapeutic dose for the treatment of chronic diarrhea in a pediatric population has not been established.

Adults: The recommended initial dose is 4 mg (two capsules) followed by 2 mg (one capsule) after each unformed stool until diarrhea is controlled, after which t”he dosage of IMODIUM® should be reduced to meet individual requirements. When the optimal daily dosage has been established, this amount may then be administered as a single dose or in divided doses.

The average daily maintenance dosage in clinical trials was 4 to 8 mg (two to four capsules). A dosage of 15 mg (eight capsules) was rarely exceeded. lf clinical improvement is not observed after treatment with 16 mg per day for at least 10 days, symptoms are unlikely to be controlled by further administration. IMODIUM® administration may be continued if diarrhea cannot be adequately controlled with diet or specific treatment.

Children under 2 Years: The use of lmodium in children under 2 years is not recommended. There have been rare reports of paralytic ileus associated with abdominal distention. Most of these reports occurred in the setting of acute dysentery, overdose, and with very young children less than two years of age.

Elderly: No formal pharmacokinetic studies were conducted in elderly subjects. However, there were no major differences reported in the drug disposition in elderly patients with diarrhea relative to young patients. No dosage adjustment is required in the elderly.

IMODIUM FOR DOGS

Imodium for diarrheaSome dogs with certain types of diarrhea can take lmodium, but in other cases, giving your dog lmodium can lead to potentially serious side effebts like constipation, sedation (which can be severe), bloat and pancreatitis.

PRECAUTIONS

  • Your dog is a herding breed (like a Collie, Sheltie or Australian shepherds). These dogs may carry a mutant form of the ABCBL-1L (MDRI) gene that dramatically limits their ability to break down some types of drugs, including lmodium. Dogs can be tested for the MDRl gene, but unless you are sure of your dog’s status, abide by the veterinary adage, “White Feet = Don’t Treat.”
  • Your dog’s diarrhea could potentially be caused by an infection (e.g. Clostridium perfringens bacteria) or toxins like those found in some types of poisonous mushrooms. Diarrhea is the body’s way of flushing out these offenders, so the last thing you want to do is eliminate that process.
  • Your dog has another health condition (e.g. liver or kidney disease, Addison’s disease, difficulty breathing, hypothyroidism, or a head injury) that could make them more susceptible to the side effects of lmodium. Also, avoid lmodium if your dog has abdominal pain, is vomiting profusely, is very old or very young, or is significantly debilitated in any way.

lf none of these conditions are relevant to your pet’s situation, call your veterinarian to see if he or she thinks giving your dog lmodium is a good idea. Your vet may recommend a different dose (or different treatment altogether), but something along the lines of 0.1 mg/kg of lmodium given twice a day is typical. lf you do the math, this means that a ten-pound dog might receive a dose of 0.4 mg of lmodium while a dog who weighs 50 pounds could be given around 2 mg.lmodium tablets contain 2 mg of the drug and should only,be given to larger dogs. Liquid lmodium is typically available in a concentration of 1 mg/5 mL (0.2 mg/ml), so is a better choice for smaller dogs.

Always confirm the correct dose of lmodium with your veterinarian since it may be adjusted based on your dog’s unique situation. lf you are wary of giving your dog lmodium, other at-home options to treat mild dog diarrhea include probiotic supplements, dietary therapy, kaolin/pectin products, or PePto-Bismol.

IMODIUM FOR KIDS

You should be sure to get the affirmative words from your child’s doctor before giving lmodium to your child. This is particularly important if your child is younger than 6 years. lmodium should not be used in children who are younger than 2 years. lf your child has a medical condition that’s causing the diarrhea, talk to your child’s doctor first before using lmodium. Do not use lmodium to treat your child for more than one day. If your child has diarrhea that lasts more than one day, stop giving them lmodium and call their doctor right away.

You should also call your child’s doctor if your child has any of the following symptoms:

  • a fever of 102″F (39″C) or higher
  • stools that are black and tarry or stools with blood or pus

 

DOSAGE AND LENGTH OF USE

Younger children (ages 2-5 years) should only take the liquid form of lmodium. Children who are older than 6 years may take the capsules or tablets as well. lf your child can’t swallow a capsule, you can open the capsule and sprinkle it on food. The food should be something that the medication can mix with, such as applesauce.

The dosage of lmodium that you give your child should be based on your child’s weight or age. You can use the following table as a guide, but it’s better to ask your pharmacist or child’s doctor for a specific dosage.

IMODIUM dosage

 

Side effects in children

Imodium can affect children differently than it can affect adults. You should watch your child closely for side effects. Side effects of lmodium in children can include:

  • constipation
  • dry mouth
  • gas
  • nausea
  • vomiting
  • headache
  • stomach pain or cramps
  • stomach enlargement
  • colic or repeated bouts of crying in younger children

lf your child has constipation or an enlarged stomach, stop using lmodium and call their doctor.

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