Histamine can produce symptoms of itching, sneezing, runny nose and watery eyes. Diphenhydramine/Benadryl is an antihistamine which blocks the effects of the naturally occurring chemical known as histamine in the body. As an antihistamine, it dilutes the effects of natural chemical histamine in the body. Diphenhydramine/Benadryl is used to cure itching, watery eyes, sneezing, runny nose, skin rash watery eyes, hives, skin rash, cold or any other allergy symptoms. Diphenhydramine/Benadryl is also used to induce sleep, cure motion sickness, and to treat certain Parkinson’s disease symptoms.

Caution must be implemented in driving, or performing any hazardous activities when taking diphenhydramine because it may cause drowsiness or dizziness. Also, use alcohol carefully. Alcohol may increase drowsiness and dizziness while on diphenhydramine dose. Do not give this medication to a child younger than 2 years old.

When administering diphenhydramine/Benadryl on a child, always ask a doctor before giving it as a cough or cold medicine. The misuse of a cough or cold medicine in children can lead to death in many young children. You should not use diphenhydramine if you are hypersensitive or allergic to it. If you have other medical conditions such as below:

  • Blockage in the digestive tract either the stomach or intestine
  • Liver or Kidney disorder
  • Asthmas
  • Breathing disorder
  • Chronic obstructive pulmonary disease (COPD)
  • Heart disease
  • Glaucoma
  • Chronic Bronchitis
  • Bladder/Urinary problems
  • Cough with mucus or caused as a result of smoking
  • Thyroid disorder

If you have FDA category B, it is very important to seek medical advice from a doctor or pharmacist if it is appropriate for you to take diphenhydramine. Although, Diphenhydramine is not likely to harm an unborn baby, but should not be used without a doctor’s advice if you are pregnant.

Diphenhydramine can diffuse into breast milk and may harm a breastfeeding infant, therefore, you are expected not take the medication while breastfeeding. Older adults may be more susceptible to the side effects from this medicine. Use diphenhydramine precisely as instructed on the label, or as ordered by your doctor. Do not take in larger or smaller dose or longer than required. When Diphenhydramine is used to treat cold or allergy, it is usually taken only for a short period until your symptoms clear up. lt is not advisable to administer Diphenhydramine to a child under the age 2 years.

Diphenhydramine/Benadryl Dosage

The medication is used to treat various illness and allergic reactions and the dosage is based on the type of condition experienced by an individual.

Standard Adult Dose for Cough: 25 mg orally every 4 hours as required, not to go above 150 mg daily

Standard Adult Dose for itching (Pruritus): 25 to 50 mg orally every 4 to 6 hours as required, not to go above 3OO mg/24 hours.

Standard Adult Dose of Diphenhydramine for Hives (Urticaria): 25 to 50 mg orally every 4 to 6 hours as required, not to go above 3OO mg/24 day.

Standard Adult Dose of Diphenhydramine for Symptoms of Cold: Use 25 to 50 mg orally every 4 to 6 hours as required, not to go above 300 mg/day.

Standard Adult Dose of Diphenhydramine for Extrapyramidal Symptoms:

Parenteral: 10 to 50 mg administered intravenously (IV) or Intramuscularly (IM) as needed. You may increase the dose to 100 mg if necessary. But the maximum daily dose is 400 mg

Oral: 25 to 50 mg orally every 6 to 8 hours. Before exposure to motion, administer the first dose 30 minutes earlier and repeat before meals and upon retiring for the duration of the journey.

For liquid medicine , use a dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

Standard Children Dose for Allergic Rhinitis:

DIPHENHYDRAMINE OR BENADRYLFrom 2 years old but less than 5 years: Administer 6.25 mg orally every 4to 5 hours, not to go above 37.5 mg/24 hours.

From 6 years old but less than 12 years: Administer 12.5 to 25 mg orally every 4 to 6 hours, not to go above 150 mg/day.

From 12 years and above: Administer 25 to 50 mg orally every 4 to 6 hours, not to go above 300 mg/day.

Standard Children Dose for Cold Symptoms:

From 2 years old but less than 5 years: Administer 5.25 mg orally every 4 to 6 hours, not to go above 37.5 mg/day.

From 5 years old but less than L2 years: Use 12.5 to 25 mg orally every 4 to 5 hours, not to go above L5O mg/24 hour.

From 72 years and above: Use 25 to 50 mg orally every 4 to 6 hours, not to go above 300 mg/day.

Standard Children Dose for Motion Sickness:

From 2 years old but less than 5 years: Administer 5.25 mg orally every 4 to 5 hours, not to go above 37.5 mg/day.

From 6 years old but less than 12 years: Administer 12.5 to 25 mg orally every 4 to 6 hours, not to go above 150 mg/day.

From 12 years and above: 25 to 50 mg orally every 4 to 6 hours, not to go above 300 mg/day

Note: Before you are in any condition which can stimulate motion sickness (such as boat or plane travel, park rides, or a long car drive) take diphenhydramine 30 minutes earlier. Continue to take diphenhydramine after meals and before bedtime for the rest of the time you will be in a condition of the motion-sickness.

Standard Children Dose for Insomnia:

From 12 years and above : 25 to 50 mg orally at bedtime. To aid sleep, use diphenhydramine within 30 minutes ahead of bedtime.

Standard Children Dose for Cough:

From 2 years old but less than 6 years: 5.25 mg orally every 4 to 6 hours, not to go above 37.5 mg/day.

From 6 years old but less than 12 years: Administer 12.5 to 25 mg orally every 4 to 6 hours, not to be more than 75 mg/day.

From 1-2 years and above: 25 mg orally every 4 to 5 hours, not to go above 150 mg/day.

Standard Children Dose for Dystonic reactions: 1 to 2 mg/kg (maximum of 50 mg) administered intravenously (IV) or intramuscularly (IM).

Standard Children Dose for Allergic Reaction: Between 1 to 12 years: 5 mg per kg daily administered intramuscularly (IM), intravenously (IV) or orally, in equally divided doses every 6 to 8 hours, not to exceed 300 mg/day.

In acute hypersensitivity reactions: 1 to 2me/kg IV or IM (maximum of 50 mg) [Advanced Paediatric Life Support]

If symptoms persist after 7 days of treating with the medication or other symptoms such as a headache, skin rash or any other is accompanied, it is advisable to seek medical attention from your doctor.

Note:

1. Ask a physician or pharmacist before using this medication if you are also using any other drugs, including over- the counter or prescribed, herbal mixtures and vitamins. Some adverse effect can be initiated when used in combination with other drugs.

2. Store at room temperature away from heat and moisture.

3. Since the medication is used as required, you may not be on a dosing schedule but if you are on a schedule and you miss any dose, you should take it immediately you remember.

4. You can also skip the missed dose if the time for the next dose is close.

5. Do you take additional medication to make up for the missed dose.

Diphenhydramine/Benadryl side effects

DIPHENHYDRAMINE / BENADRYL side effect - dizzinessStop using diphenhydramine and call your doctor at once if you notice the following:

  • Pounding or trembling heartbeats
  • Difficult or painful urination or little or no urination
  • Difficult feeling like you might pass out
  • Uncontrollable movement of your tongue or stiffness of your neck and jaw

Common side effects of diphenhydramine may include

  • Dizziness, drowsiness and loss of coordination
  • Dry throat, nose, or mouth
  • Stomach upset or constipation
  • Dry eyes, and blur vision
  • Swelling face or lips

Get emergency medical attention if you noticed any of these signs of an allergic reaction to diphenhydramine.

Using Diphenhydramine/Benadryl for the controlling panic attacks can be useful many cases. Benadryl has an antihistamine that has a sedative effect which can aid sleeping difficulties. Also, Benadryl is made to open the sinuses, by providing an easy breathing and this can help you in ease your breath which speeds up during a panic attack.

It is wise and safe to use these medications for the purpose for which they were intended. If you become resistance to Benadryl after using to treat either panic and anxiety, then you won’t be able to put it to use when you do need it for colds or allergies. Benadryl is one of the highly recommended medications for hay fever, however, also keep in mind the side effects. The side effects vary with individuals , but the common ones are tiredness and drowsiness. Although it performs quickly to lessen reactions, but it could make you fall asleep and without caution.

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